Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52]

Catalog number HA722725

Price for HA722725

Size / count 100 µL

About this product

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

Specifications

Catalog number: HA722725
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Activin A receptor type IIB antibody Activin receptor type 2B antibody Activin receptor type IIB antibody Activin receptor type-2B antibody ActR IIB antibody ACTR-IIB antibody ActRIIB antibody ACVR 2B antibody ACVR2B antibody AVR2B_HUMAN antibody HTX4 antibody MGC116908 antibody
Abbreviation: ACVR2B
Swiss Prot: Q13705 Human, P27040 Mouse, P38445 Rat
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within
Isotype: IgG
Clone: JE33-52
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: 293T cell lysate, K-562 cell lysate, Jurkat cell lysate, HeLa cell lysate, Mouse heart tissue lysate, Rat heart tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 58 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52]?

The catalog number for Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52] is HA722725.

What sizes are available for Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52]?

Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52] is available in the following size(s): 100 µL.

Is Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52] in stock?

Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Activin Receptor Type IIB / ACVR2B Recombinant Rabbit Monoclonal Antibody [JE33-52] used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.