UBASH3A-Specific antibody

Specifications

Catalog number

FNab09150

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

UBASH3A gene encodes ubiquitin-associated and SH3 domain-containing protein A (UBASH3A) also known as T-cell ubiquitin ligand 1 (TULA1) which is one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. UBASH3A gene expression is limited to only a few tissues, with its highest expression in spleen, peripheral blood leukocytes, and bone marrow. UBASH3A protein is associated with c-Cbl and ubiquitylated proteins and has been implicated in the regulation of signaling mediated by protein-tyrosine kinases oth family members can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells via its interaction with apoptosis-inducing factor (AIF) . This antibody is UBASH3A-specific.

Synonyms

Ubiquitin-associated and SH3 domain-containing protein A|Cbl-interacting protein 4 (CLIP4) |Suppressor of T-cell receptor signaling 2 (STS-2) |T-cell ubiquitin ligand 1 (TULA-1) |UBASH3A|STS2

Gene ID

53347

UniProt

P57075

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Ubiquitin associated and SH3 domain containing, A

Target

UBASH3A

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF, IP

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IF: 1:10-1:100; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

69 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IF, IP