Product details
Catalog number HA722877
Price for HA722877
Size / count 100 µL
Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage. In addition, plays a role in immune response and possesses antiviral activity against various viruses such as vesicular stomatitis virus, influenza A virus (H1N1) and human herpes virus 1. Mechanistically, translocates from the cytoplasm into the cell nucleus upon virus infection to influence NF-kappa-B activities.
The catalog number for Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) is HA722877.
Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.
Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.
Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases suc
Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.
Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.
Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.