• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture)

Catalog number HA722877

Price for HA722877

Sign In for Pricing

Size / count 100 µL

About this product

Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage. In addition, plays a role in immune response and possesses antiviral activity against various viruses such as vesicular stomatitis virus, influenza A virus (H1N1) and human herpes virus 1. Mechanistically, translocates from the cytoplasm into the cell nucleus upon virus infection to influence NF-kappa-B activities.

Specifications

Catalog number
HA722877
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CHDS6 antibody Matrix metalloproteinase 3 antibody Matrix metalloproteinase 3 preproprotein antibody Matrix metalloproteinase-3 antibody MGC126102 antibody MGC126103 antibody MGC126104 antibody MMP 3 antibody MMP-3 antibody MMP3 antibody MMP3_HUMAN antibody Proteoglycanase antibody SL-1 antibody SL1 antibody STMY antibody STMY1 antibody STR1 antibody Stromelisin 1 antibody Stromelysin 1 antibody Stromelysin 1 progelatinase antibody Stromelysin-1 antibody Transin 1 antibody Transin-1 antibody
Abbreviation
Stromelysin-1 SL-1 Matrix metalloproteinase-3 (MMP-3) Transin-1 MMP3 STMY1
Swiss Prot
P08254 Human
Cellular Locus
Secreted
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human MMP-3 aa18-477 (HA210853).
Isotype
IgG
Clone
PSH07-61
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Cap)
Positive Control
Recombinant Human MMP-3 protein (HA210853).
Concentration
1 mg/mL
Dilution
ELISA (Cap): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH07-62] to Human MMP-3 antibody (Detector) (HA722878) and recombinant Human MMP-3 protein as the standard (HA210853). The reference range value is 41.2-10,000 pg/ml.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture)?

The catalog number for Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) is HA722877.

What sizes are available for Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture)?

Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.

Is Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) in stock?

Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-61] - BSA and Azide free (Capture) used for?

Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases suc

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

You Might Also Like
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880460-100
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880177-100
CD34 (ICO-115), CF568 conjugate, 0.1mg/mL
CD34 (ICO-115), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680039-100
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC400178-500
CD8 (C8/468), CF740 conjugate, 0.1mg/mL
CD8 (C8/468), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740468-100
UACA / Nucling (AE-5), CF405S conjugate, 0.1mg/mL
UACA / Nucling (AE-5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040956-500
TRP1 (Tyrosinase Related Protein 1) (TYRP1/807), CF594 conjugate, 0.1mg/mL
TRP1 (Tyrosinase Related Protein 1) (TYRP1/807), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940807-100