PSMD13 Recombinant Rabbit Monoclonal Antibody [PSH0-52]

About this product

26S proteasome non-ATPase regulatory subunit 13 is an enzyme that in humans is encoded by the PSMD13 gene. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.

Specifications

Catalog number

HA721399

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

26S proteasome non ATPase regulatory subunit 13 antibody 26S proteasome non-ATPase regulatory subunit 13 antibody 26S proteasome regulatory subunit p40.5 antibody 26S proteasome regulatory subunit RPN9 antibody 26S proteasome regulatory subunit S11 antibody 26S proteasome subunit p40.5 antibody HSPC027 antibody P40.5 antibody Proteasome (prosome, macropain) 26S subunit, non ATPase, 13 antibody Proteasome 26S subunit, non-ATPase 13 antibody PSD13_HUMAN antibody psmD13 antibody Rpn9 antibody S11 antibody

Abbreviation

PSMD13

Swiss Prot

Q9UNM6 Human, Q9WVJ2 Mouse, B0BN93 Rat

Cellular Locus

Proteasome, cytosol, extracellular region, nucleoplasm, nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human PSMD13 aa 1-150/376.

Isotype

IgG

Clone

PSH0-52

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

HeLa cell lysate, Jurkat cell lysate, HepG2 cell lysate, SiHa cell lysate, HEK-293 cell lysate, SH-SY5Y cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, human brain tissue, rat brain tissue, HeLa.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:200 ;IF-Cell: 1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 43 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes