CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45]

Catalog number HA722991

Price for HA722991

Size / count 100 µL

About this product

Calcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and calcitonin‑receptor‑stimulating peptide. CGRP is produced in both peripheral and central neurons. It is a potent peptide vasodilator and can function in the transmission of nociception. In the spinal cord, the function and expression of CGRP may differ depending on the location of synthesis. CGRP is derived mainly from the cell bodies of motor neurons when synthesized in the ventral horn of the spinal cord and may contribute to the regeneration of nervous tissue after injury. Conversely, CGRP is derived from dorsal root ganglion when synthesized in the dorsal horn of the spinal cord and may be linked to the transmission of pain. In the trigeminal vascular system, the cell bodies of the trigeminal ganglion are the main source of CGRP. CGRP is thought to play a role in cardiovascular homeostasis and nociception. In the heart, CGRP acts as a chronotrope by increasing heart rate. Apart from these attributes, CGRP is known to modulate the autonomic nervous system and plays a role in ingestion. CGRP has moderate effects on calcium homeostasis compared to its extensive actions in other areas, such as the autonomic nervous system.

Specifications

Catalog number: HA722991
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Calcitonin/calcitonin related polypeptide alpha antibody Alpha type CGRP antibody Beta type CGRP antibody CALC1 antibody CALC2 antibody CALCA antibody CALCB antibody Calcitonin 1 antibody Calcitonin 2 antibody Calcitonin gene related peptide I antibody Calcitonin gene related peptide II antibody Calcitonin related polypeptide alpha antibody Calcitonin related polypeptide beta antibody CGRP antibody CGRP I antibody CGRP II antibody CGRP1 antibody CGRP2 antibody CT antibody Katacalcin antibody KC antibody
Abbreviation: Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I (CGRP-I), CALCA, CALC1, Calcitonin gene-related peptide 2, Beta-type CGRP (Beta-CGRP), Calcitonin gene-related peptide II (CGRP-II), CALCB, CALC2
Swiss Prot: P06881 Human, P10092 Human, P70160 Mouse, Q99JA0 Mouse, P01256 Rat, P01257 Rat
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within rat CGRP aa 1-128.
Isotype: IgG
Clone: PSH08-45
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC, IHC-Fr
Positive Control: TT cell lysate, TT, mouse spinal cord tissue, rat spinal cord tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:200-1:1,000 ;FC: 1:10,000 ;IHC-Fr: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 14 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45]?

The catalog number for CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45] is HA722991.

What sizes are available for CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45]?

CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45] is available in the following size(s): 100 µL.

Is CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45] in stock?

CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CGRP Recombinant Rabbit Monoclonal Antibody [PSH08-45] used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.