TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99]

Catalog number HA721918

Price for HA721918

Size / count 100 µL

About this product

Tripartite motif-containing protein 29 (TRIM29, ATDC) was isolated as a candidate gene by its ability to complement the radiosensitivity defect of an ataxia-telangiectasia (AT) cell line. This putative transcription regulator belongs to the TRIM (tripartite motif) protein family that is characterized by highly conserved amino-terminal RING finger, B-box, and coiled-coil domains. The TRIM29 protein binds and sequesters cytosolic p53, repressing expression of p53 target genes including p21 and Noxa by preventing p53 from entering the nucleus. Expression of TRIM29 inhibits p53 function and results in increased cell proliferation. TRIM29 enhances tumor growth and metastasis in vivo and high TRIM29 levels are seen in most invasive pancreatic cancers. The oncogenic effect of TRIM29 appears to require β-catenin as expression of both proteins is elevated in pancreatic cancer cell lines and tissues .

Specifications

Catalog number: HA721918
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Ataxia telangiectasia group D associated protein antibody Ataxia telangiectasia group D-associated protein antibody ATDC antibody FLJ36085 antibody TRI29_HUMAN antibody TRIM 29 antibody TRIM29 antibody Tripartite motif containing 29 antibody Tripartite motif containing protein 29 antibody Tripartite motif protein 29 antibody Tripartite motif protein TRIM29 antibody Tripartite motif-containing protein 29 antibody
Abbreviation: Tripartite motif-containing protein 29 Ataxia telangiectasia group D-associated protein TRIM29 ATDC
Swiss Prot: Q14134 Human, Q8R2Q0 Mouse,
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human TRIM29 aa 1-588 / 588.
Isotype: IgG
Clone: PSH02-99
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, FC
Positive Control: A431 cell lysate, SiHa cell lysate, SW1990 cell lysate, HT-29 cell lysate, A431, human prostate tissue, human skin tissue, mouse skin tissue, rat skin tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IHC-P: 1:500-1:2,000 ;IF-Cell:1:100 ;FC:1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 66 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99]?

The catalog number for TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99] is HA721918.

What sizes are available for TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99]?

TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99] is available in the following size(s): 100 µL.

Is TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99] in stock?

TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TRIM29 Recombinant Rabbit Monoclonal Antibody [PSH02-99] used for?

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.