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Product details

CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71]

Catalog number HA721579

Price for HA721579

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Size / count 100 µL

About this product

CD30, also known as TNFRSF8 (TNF receptor superfamily member 8), is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. It is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. CD30 is associated with anaplastic large cell lymphoma. It is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors. CD30 and CD15 are also expressed on Reed-Sternberg cells typical for Hodgkin's lymphoma.

Specifications

Catalog number
HA721579
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CD 30 antibody CD30 antibody CD30 antigen antibody CD30L receptor antibody Cytokine receptor CD30 antibody D1S166E antibody KI 1 antibody KI 1 antigen antibody Ki-1 antigen antibody KI1 antibody Lymphocyte activation antigen CD30 antibody TNFRSF 8 antibody Tnfrsf8 antibody TNR8_HUMAN antibody Tumor necrosis factor receptor superfamily member 8 antibody
Abbreviation
TNFRSF8, CD30, D1S166E
Swiss Prot
P28908 Human
Cellular Locus
Cell membrane; Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human CD30 aa 546-595 / 595.
Isotype
IgG
Clone
JE57-71
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HDLM-2 cell lysate, human hodgkin lymphoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 64 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71]?

The catalog number for CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71] is HA721579.

What sizes are available for CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71]?

CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71] is available in the following size(s): 100 µL.

Is CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71] in stock?

CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD30 Recombinant Rabbit Monoclonal Antibody [JE57-71] used for?

CD30, also known as TNFRSF8 (TNF receptor superfamily member 8), is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the si

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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