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Product details

Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector)

Catalog number HA722101

Price for HA722101

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Size / count 100 µL

About this product

Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279). PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell surface receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self-tolerance by suppressing T cell inflammatory activity. This prevents autoimmune diseases, but it can also prevent the immune system from killing cancer cells. PD-1 is an immune checkpoint and guards against autoimmunity through two mechanisms. First, it promotes apoptosis (programmed cell death) of antigen-specific T-cells in lymph nodes. Second, it reduces apoptosis in regulatory T cells (anti-inflammatory, suppressive T cells). PD-1 inhibitors, a new class of drugs that block PD-1, activate the immune system to attack tumors and are used to treat certain types of cancer. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells. PD-1 binds two ligands, PD-L1 and PD-L2.

Specifications

Catalog number
HA722101
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CD279 antibody CD279 antigen antibody hPD 1 antibody hPD l antibody hPD-1 antibody hSLE1 antibody PD 1 antibody PD-1 antibody PD1 antibody PDCD 1 antibody PDCD1 antibody PDCD1_HUMAN antibody Programmed cell death 1 antibody Programmed cell death 1 protein antibody Programmed cell death protein 1 antibody Protein PD 1 antibody Protein PD-1 antibody SLEB2 antibody Systemic lupus erythematosus susceptibility 2 antibody
Abbreviation
Programmed cell death protein Protein PD-1 mPD-1 CD279 Pdcd Pd1
Swiss Prot
Q02242 Mouse
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant protein within Mouse PD1 aa 25-167 (Q02242).
Isotype
IgG
Clone
PSH04-18
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Det)
Positive Control
Recombinant standard Mouse PD1 protein (HA210625).
Concentration
1 mg/mL
Dilution
ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH04-17] to Mouse PD1 (Capture) (HA722100) and recombinant standard Mouse PD1 protein (HA210625). The reference range value is 12.3-3000pg/ml.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 31.8 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector)?

The catalog number for Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector) is HA722101.

What sizes are available for Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector)?

Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector) in stock?

Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mouse PD1 Recombinant Rabbit Monoclonal Antibody [PSH04-18] - BSA and Azide free (Detector) used for?

Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279). PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell surface receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating t

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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