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Product details

Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector)

Catalog number HA722498

Price for HA722498

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Size / count 100 µL

About this product

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. A form of basal ganglia calcification, an autosomal dominant condition characterized by symmetric calcification in the basal ganglia and other brain regions. Affected individuals can either be asymptomatic or show a wide spectrum of neuropsychiatric symptoms, including parkinsonism, dystonia, tremor, ataxia, dementia, psychosis, seizures, and chronic headache. Serum levels of calcium, phosphate, alkaline phosphatase and parathyroid hormone are normal. The neuropathological hallmark of the disease is vascular and pericapillary calcification, mainly of calcium phosphate, in the affected brain areas.

Specifications

Catalog number
HA722498
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Becaplermin antibody c sis antibody FLJ12858 antibody Oncogene SIS antibody PDGF 2 antibody PDGF B chain antibody PDGF Beta antibody PDGF subunit B antibody PDGF-2 antibody PDGF2 antibody Pdgfb antibody PDGFB_HUMAN antibody Platelet derived growth factor 2 antibody Platelet derived growth factor B chain antibody Platelet derived growth factor beta antibody Platelet derived growth factor beta polypeptide (oncogene SIS) antibody Platelet derived growth factor beta polypeptide (simian sarcoma viral (v sis) oncogene homolog) antibody Platelet derived growth factor beta polypeptide antibody Platelet-derived growth factor B chain antibody Platelet-derived growth factor beta polypeptide antibody Platelet-derived growth factor subunit B antibody Proto-oncogene c-Sis antibody Simian sarcoma viral (v sis) oncogene homolog antibody SIS antibody SSV antibody v sis platelet derived growth factor beta polypeptide antibody
Abbreviation
Platelet-derived growth factor subunit B PDGF subunit B PDGF-2 Platelet-derived growth factor B chain Platelet-derived growth factor beta polypeptide Proto-oncogene c-Sis Becaplermin PDGFB PDGF2, SIS
Swiss Prot
P01127 Human
Cellular Locus
Secreted
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human PDGF-B aa 82-190.
Isotype
IgG
Clone
PSH05-99
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Det)
Positive Control
Recombinant standard Human PDGF-BB protein (HA210859).
Concentration
1 mg/mL
Dilution
ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH05-98] to Human PDGF-BB (Capture) (HA722497) and recombinant standard Human PDGF-BB protein (HA210859) as the standard. The reference range value is 30.9-2500 pg/ml.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 27 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector)?

The catalog number for Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector) is HA722498.

What sizes are available for Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector)?

Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector) in stock?

Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human PDGF-BB Recombinant Rabbit Monoclonal Antibody [PSH05-99] - BSA and Azide free (Detector) used for?

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the c

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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