- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![Stra8 Recombinant Rabbit Monoclonal Antibody [PSH04-55] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea82691/imageurl/ha722154.webp)
Select the image to view it full size.
Product details
Catalog number HA722154
Price for HA722154
Size / count 100 µL
The signaled by retinoic acid 8 (Stra8) gene is activated only upon stimulation by retinoic acid and expresses a cytoplasmic protein in the gonads of male and female vertebrates. This protein functions to initiate the transition between mitosis and meiosis, aiding in spermatogenesis and oogenesis. In females, its signaling begins 12.5 days after conception, is localized in the primordial germ cells of female ovaries, and ushers in the first stage of meiosis. Male expression begins postnatally and continues throughout life, matching the need of spermatogenesis compared to the limited window of oogenesis in females. Sperm of mice that had induced null mutations for Stra8 gene were able to undergo mitotic divisions, and while some sperm were able to transition into the early stages of meiosis I, but could not transition into further sub-stages of meiosis I. Errors in chromosome pairing and chromosome condensation were observed following these failures. In female mice, loss of Stra8 signaling shows failure to enter into meiosis. Both males and females are left infertile if Stra8 signaling is absent.
The catalog number for Stra8 Recombinant Rabbit Monoclonal Antibody [PSH04-55] is HA722154.
Stra8 Recombinant Rabbit Monoclonal Antibody [PSH04-55] is available in the following size(s): 100 µL.
Stra8 Recombinant Rabbit Monoclonal Antibody [PSH04-55] is currently made to order / not held in immediate stock. Contact us for lead time.
The signaled by retinoic acid 8 (Stra8) gene is activated only upon stimulation by retinoic acid and expresses a cytoplasmic protein in the gonads of male and female vertebrates. This protein functions to initiate the transition between mitosis and meiosis, aiding in spermatogenesis and oogenesis. I
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.
Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.
