eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R]

Catalog number HA601294

Price for HA601294

Size / count 100 µL

About this product

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis.

Specifications

Catalog number: HA601294
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: b (2)gcn antibody B (2)GCN homolog antibody B4 integrin interactor antibody Binding protein of beta-4 integrin antibody CAB antibody eIF-6 antibody EIF3A antibody EIF6 antibody Eukaryotic translation initiation factor 3A antibody Eukaryotic translation initiation factor 6 antibody IF6_HUMAN antibody Integrin beta 4 binding protein antibody ITGB4BP antibody OK/SW-cl.27 antibody p27 beta 4 integrin binding protein antibody p27 (BBP) antibody p27BBP antibody RP4-614O4.1 antibody
Abbreviation: EIF6
Swiss Prot: P56537 Human, O55135 Mouse, Q3KRD8 Rat
Cellular Locus: Cytoplasm, Nucleus, nucleolus.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human eIF-6 aa 1-200.
Isotype: IgG1
Clone: A6A2-R
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: WB
Positive Control: HeLa cell lysate, HepG2 cell lysate, RAW264.7 cell lysate, NIH/3T3 cell lysate, mouse testis tissue lysate, rat testis tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 27 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R]?

The catalog number for eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R] is HA601294.

What sizes are available for eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R]?

eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R] is available in the following size(s): 100 µL.

Is eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R] in stock?

eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is eIF-6 Recombinant Mouse Monoclonal Antibody [A6A2-R] used for?

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.