Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture)

Catalog number HA722985

Price for HA722985

Size / count 100 µL

About this product

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. Induces rapid UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets.

Specifications

Catalog number: HA722985
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: C9orf26 CHROMOSOME 9 OPEN READING FRAME 26 DKFZp586H0523 DVS27 DVS27 related protein IL 1F11 IL 33 IL-1F11 IL-33 IL1F11 IL33 IL33_HUMAN Interleukin 1 family member 11 Interleukin 33 INTERLEUKIN 33 NFHEV Interleukin 33 precursor Interleukin-1 family member 11 Interleukin-33 (109-270) Interleukin33 NF HEV NF-HEV NFEHEV NFHEV Nuclear factor for high endothelial venules Nuclear factor from high endothelial venules OTTHUMP00000021041 RP11 575C20.2
Abbreviation: Interleukin-33 IL-33 Il33
Swiss Prot: Q8BVZ5 Mouse
Cellular Locus: Nucleus. Chromosome. Cytoplasmic vesicle, secretory vesicle. Secreted.
Host: Rabbit
Species Reactivity: Mouse
Immunogen: Recombinant protein within Mouse IL-33 aa 109-266 (HA210768).
Isotype: IgG
Clone: PSH08-41
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Cap)
Positive Control: Recombinant Mouse IL-33 protein (HA210768).
Concentration: 1 mg/mL
Dilution: ELISA (Cap): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH08-42] to Mouse IL-33 antibody (Detector) (HA722986) and Recombinant Mouse IL-33 protein (HA210768) as the standard. The reference range value is 15.6-2,000 pg/ml.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture)?

The catalog number for Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture) is HA722985.

What sizes are available for Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture)?

Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.

Is Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture) in stock?

Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mouse IL-33 Recombinant Rabbit Monoclonal Antibody [PSH08-41] - BSA and Azide free (Capture) used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.