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![Human Beta Nerve Growth Factor Recombinant Rabbit Monoclonal Antibody [PSH07-81] - BSA and Azide free (Detector) — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81661/imageurl/ha722904.webp)
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Product details
Catalog number HA722904
Price for HA722904
Size / count 100 µL
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (Probable) (PubMed:20978020). The immature NGF precursor (proNGF) functions as a ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI. Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form. A form of hereditary sensory and autonomic neuropathy, a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self-mutilation. The autonomic involvement is variable.
The catalog number for Human Beta Nerve Growth Factor Recombinant Rabbit Monoclonal Antibody [PSH07-81] - BSA and Azide free (Detector) is HA722904.
Human Beta Nerve Growth Factor Recombinant Rabbit Monoclonal Antibody [PSH07-81] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.
Human Beta Nerve Growth Factor Recombinant Rabbit Monoclonal Antibody [PSH07-81] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (Probable) (PubMed:209780
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
