Product details
Catalog number HA722818
Price for HA722818
Size / count 100 µL
ERO1-like protein alpha is a protein that in humans is encoded by the ERO1L gene. Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins 1. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin.
The catalog number for ERO1L Recombinant Rabbit Monoclonal Antibody [PSH07-30] is HA722818.
ERO1L Recombinant Rabbit Monoclonal Antibody [PSH07-30] is available in the following size(s): 100 µL.
ERO1L Recombinant Rabbit Monoclonal Antibody [PSH07-30] is currently made to order / not held in immediate stock. Contact us for lead time.
ERO1-like protein alpha is a protein that in humans is encoded by the ERO1L gene. Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds
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The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
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