ACRV1 Recombinant Rabbit Monoclonal Antibody [JE36-02]

About this product

Acrosomal protein SP-10 is a protein that in humans is encoded by the ACRV1 gene. This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.

Specifications

Catalog number

HA722543

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Acrosomal protein SP 10 antibody Acrosomal protein SP-10 antibody Acrosomal vesicle protein 1 antibody ACRV1 antibody ASPX_HUMAN antibody D11S4365 antibody Msa63 antibody SP 10 antibody Sp10 antibody SPACA2 antibody Sperm protein 10 antibody

Abbreviation

ACRV1

Swiss Prot

P26436 Human, P50289 Mouse,

Cellular Locus

Cytoplasmic vesicle, secretory vesicle, acrosome.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within

Isotype

IgG

Clone

JE36-02

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

LNCaP cell lysate, RWPE-1 cell lysate, HepG2 cell lysate, Mouse testis tissue lysate, Rat testis tissue lysate, human testis tissue, mouse epididymis tissue, mouse testis tissue, rat epididymis tissue, rat testis tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:200-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 28 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes