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Product details

Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86]

Catalog number HA721744

Price for HA721744

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Size / count 100 µL

About this product

Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. Required for proper localization of non-farnesylated prelamin-A/C. Together with NEMP1, contributes to nuclear envelope stiffness in germ cells. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.

Specifications

Catalog number
HA721744
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
EDMD antibody Emd antibody EMD_HUMAN antibody Emerin antibody Emery Dreifuss muscular dystrophy antibody STA antibody
Abbreviation
EMD, EDMD, STA
Swiss Prot
P50402 Human
Cellular Locus
Nucleus inner membrane, Nucleus outer membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human Emerin aa 1-200 / 254.
Isotype
IgG
Clone
PSH01-86
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
HeLa cell lysate, HEK-293 cell lysate, HepG2 cell lysate, MCF7 cell lysate, A549 cell lysate, K-562 cell lysate, human thyroid tissue, A431 cell lysate, Jurkat cell lysate, Daudi cell lysate, human breast tissue, human ovary cancer tissue, HeLa.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 29 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86]?

The catalog number for Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86] is HA721744.

What sizes are available for Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86]?

Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86] is available in the following size(s): 100 µL.

Is Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86] in stock?

Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Emerin Recombinant Rabbit Monoclonal Antibody [PSH01-86] used for?

Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulat

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

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