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Product details

SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag

Catalog number SPD-S52H8-100ug

Discontinued

Price for SPD-S52H8-100ug

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Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

SARS-CoV-2 S protein RBD (R408I), His Tag (SPD-S52H8) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1 (R408I)).

Specifications

Catalog number
SPD-S52H8-100ug
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region
Arg 319 - Phe 541
Host
HEK 293
Target
Spike RBD
Conjugation
Unconjugated
Tag
C-10×His
Source
SARS-CoV-2
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 S protein RBD (R408I), His Tag (Cat. No. SPD-S52H8) with a linear range of 0.5-8 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
27.0 kDa
Shipping Conditions
Room Temperature
Storage Conditions
-20°C

Frequently Asked Questions

What is the catalog number for SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag?

The catalog number for SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag is SPD-S52H8-100ug.

Is SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag in stock?

SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag?

SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag is manufactured by CRB.

What is the estimated delivery time for SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag?

Estimated delivery time for SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag is approximately 10 business day(s), depending on your location.

What is SARS-CoV-2 (COVID-19) S protein RBD (R408I), His Tag used for?

SARS-CoV-2 S protein RBD (R408I), His Tag (SPD-S52H8) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Phe 541 (Accession # QHD43416.1 (R408I)).

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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