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Product details

Caspase-5 Antibody

Catalog number F41059-0.4ML

Discontinued

Price for F41059-0.4ML

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Size / count 0.4 mL

This variant is discontinued and cannot be added to your cart.

About this product

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

Specifications

Catalog number
F41059-0.4ML
Size / count
0.4 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9007-83-4
UniProt
P51878
Host
Rabbit
Immunogen
A portion of amino acids 162-191 from the human protein was used as the immunogen for this Caspase-5 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Caspase-5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Caspase-5 antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for Caspase-5 Antibody?

The catalog number for Caspase-5 Antibody is F41059-0.4ML.

Is Caspase-5 Antibody in stock?

Caspase-5 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Caspase-5 Antibody used for?

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce tw

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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