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Product details

Phospho-MAP2 Antibody (pS1539)

Catalog number F48609-0.4ML

Discontinued

Price for F48609-0.4ML

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Size / count 0.4 mL

This variant is discontinued and cannot be added to your cart.

About this product

MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.

Specifications

Catalog number
F48609-0.4ML
Size / count
0.4 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9007-83-4
UniProt
P11137
Host
Rabbit
Immunogen
This phospho-MAP2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1539 of human MAP2.
Clonality
Polyclonal
Isotype
Ig
Applications
DB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the phospho-MAP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho-MAP2 antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for Phospho-MAP2 Antibody (pS1539)?

The catalog number for Phospho-MAP2 Antibody (pS1539) is F48609-0.4ML.

Is Phospho-MAP2 Antibody (pS1539) in stock?

Phospho-MAP2 Antibody (pS1539) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-MAP2 Antibody (pS1539) used for?

MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present,

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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