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Product details

Caspase-3 Antibody (phospho-S12)

Catalog number F48684-0.08ML

Discontinued

Price for F48684-0.08ML

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Size / count 0.08 mL

This variant is discontinued and cannot be added to your cart.

About this product

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq].

Specifications

Catalog number
F48684-0.08ML
Size / count
0.08 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9007-83-4
UniProt
P70677
Host
Rabbit
Immunogen
This phospho-Caspase-3 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS12 of mouse CASP3.
Clonality
Polyclonal
Isotype
Ig
Applications
DB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the phospho-Caspase-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho-Caspase-3 antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for Caspase-3 Antibody (phospho-S12)?

The catalog number for Caspase-3 Antibody (phospho-S12) is F48684-0.08ML.

Is Caspase-3 Antibody (phospho-S12) in stock?

Caspase-3 Antibody (phospho-S12) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Caspase-3 Antibody (phospho-S12) used for?

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic res

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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