Phospho-IKKB Antibody (pS689)

Catalog number F48703-0.4ML

Discontinued

Price for F48703-0.4ML

Size / count 0.4 mL

This variant is discontinued and cannot be added to your cart.

About this product

NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).

Specifications

Catalog number: F48703-0.4ML
Size / count: 0.4 mL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9007-83-4
UniProt: O14920
Host: Rabbit
Immunogen: This phospho-IKKB antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS689 of human IKKB.
Clonality: Polyclonal
Isotype: Ig
Applications: DB, ELISA
Format: Antigen affinity purified
Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution: Aliquot the phospho-IKKB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations: This phospho-IKKB antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for Phospho-IKKB Antibody (pS689)?

The catalog number for Phospho-IKKB Antibody (pS689) is F48703-0.4ML.

Is Phospho-IKKB Antibody (pS689) in stock?

Phospho-IKKB Antibody (pS689) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-IKKB Antibody (pS689) used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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