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Product details

Caspase-3 Antibody

Catalog number F48960-0.08ML

Discontinued

Price for F48960-0.08ML

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Size / count 0.08 mL

This variant is discontinued and cannot be added to your cart.

About this product

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Specifications

Catalog number
F48960-0.08ML
Size / count
0.08 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9007-83-4
UniProt
P42574
Host
Rabbit
Immunogen
A portion of amino acids 149-179 from the human protein was used as the immunogen for this Caspase-3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the Caspase-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Caspase-3 antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for Caspase-3 Antibody?

The catalog number for Caspase-3 Antibody is F48960-0.08ML.

Is Caspase-3 Antibody in stock?

Caspase-3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Caspase-3 Antibody used for?

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic res

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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