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Product details

mTOR Antibody (FRAP1)

Catalog number F49548-0.08ML

Discontinued

Price for F49548-0.08ML

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Size / count 0.08 mL

This variant is discontinued and cannot be added to your cart.

About this product

FRAP1/mTOR belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. It is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.

Specifications

Catalog number
F49548-0.08ML
Size / count
0.08 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9007-83-4
UniProt
P42345
Host
Rabbit
Immunogen
A portion of amino acids 2459-2488 from the human protein was used as the immunogen for this mTOR antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, IF, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the mTOR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This mTOR antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for mTOR Antibody (FRAP1)?

The catalog number for mTOR Antibody (FRAP1) is F49548-0.08ML.

Is mTOR Antibody (FRAP1) in stock?

mTOR Antibody (FRAP1) is currently made to order / not held in immediate stock. Contact us for lead time.

What is mTOR Antibody (FRAP1) used for?

FRAP1/mTOR belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. It

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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