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Product details

AMPK alpha 2 Antibody

Catalog number F50190-0.4ML

Discontinued

Price for F50190-0.4ML

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Size / count 0.4 mL

This variant is discontinued and cannot be added to your cart.

About this product

AMPK alpha 2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). It acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription. Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2. [UniProt]

Specifications

Catalog number
F50190-0.4ML
Size / count
0.4 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9007-83-4
UniProt
P54646
Host
Rabbit
Immunogen
A portion of amino acids 476-507 from the human protein was used as the immunogen for this AMPK alpha 2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the AMPK alpha 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This AMPK alpha 2 antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for AMPK alpha 2 Antibody?

The catalog number for AMPK alpha 2 Antibody is F50190-0.4ML.

Is AMPK alpha 2 Antibody in stock?

AMPK alpha 2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is AMPK alpha 2 Antibody used for?

AMPK alpha 2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). It acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm. In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph),

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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