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Product details

AMPK alpha 2 Antibody (PRKAA2)

Catalog number F50381-0.08ML

Discontinued

Price for F50381-0.08ML

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Size / count 0.08 mL

This variant is discontinued and cannot be added to your cart.

About this product

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Specifications

Catalog number
F50381-0.08ML
Size / count
0.08 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9007-83-4
UniProt
P54646
Host
Rabbit
Immunogen
A portion of amino acids 453-483 from the human protein was used as the immunogen for this AMPK alpha 2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the AMPK alpha 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This AMPK alpha 2 antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for AMPK alpha 2 Antibody (PRKAA2)?

The catalog number for AMPK alpha 2 Antibody (PRKAA2) is F50381-0.08ML.

Is AMPK alpha 2 Antibody (PRKAA2) in stock?

AMPK alpha 2 Antibody (PRKAA2) is currently made to order / not held in immediate stock. Contact us for lead time.

What is AMPK alpha 2 Antibody (PRKAA2) used for?

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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