alpha 2a Adrenergic Receptor Antibody

About this product

Alpha-2-adrenergic receptor(ADRA2), also known as platelet type adrenoceptor alpha-2A ,is a member of G protein-coupled receptor superfamily. This gene, which can identify a DraI RFLP of the ADRAR gene, mapped to 10q23-q25, is found in the distal region of mouse chromosome 19 and abundantly expressed in giant cell. ADRA2 acts a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. It has 3 highly homologous subtypes: ADRA2A; ADRA2B and ADRA2C. Studies in mouse suggested that both the ADRA2A and ADRA2C subtypes are required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. ADRA2A receptors inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.

Specifications

Catalog number

R30168

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9007-83-4

UniProt

P08913

Host

Rabbit

Immunogen

An amino acid sequence from the C-terminus of human alpha 2a Adrenergic Receptor (FGYCNSSLNPVIYTIFNH) was used as the immunogen for this alpha 2a Adrenergic Receptor antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P

Format

Antigen affinity purified

Buffer

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Reconstitution

After reconstitution, the alpha 2a Adrenergic Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This alpha 2a Adrenergic Receptor antibody is available for research use only.