HLA-DR Antibody (MHC II)

Catalog number V2584IHC-7ML

Discontinued

Price for V2584IHC-7ML

Size / count 7 mL

This variant is discontinued and cannot be added to your cart.

About this product

This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Specifications

Catalog number: V2584IHC-7ML
Size / count: 7 mL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9007-83-4
UniProt: P01903
Host: Mouse
Immunogen: Human peripheral blood leukocytes were used as the immunogen for the HLA-DR antibody.
Clonality: Monoclonal
Isotype: IgG2b κ
Applications: IHC-P
Format: Purified
Buffer: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution: Store the HLA-DR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations: This HLA-DR antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for HLA-DR Antibody (MHC II)?

The catalog number for HLA-DR Antibody (MHC II) is V2584IHC-7ML.

Is HLA-DR Antibody (MHC II) in stock?

HLA-DR Antibody (MHC II) is currently made to order / not held in immediate stock. Contact us for lead time.

What is HLA-DR Antibody (MHC II) used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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