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Product details

TIMP1 Recombinant Antibody

Catalog number V3596IHC-7ML

Discontinued

Price for V3596IHC-7ML

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Size / count 7 mL

This variant is discontinued and cannot be added to your cart.

About this product

TIMP1 is an inhibitory molecule that regulates matrix metalloproteinases (MMPs), and disintegrin-metalloproteinases (ADAMs and ADAMTSs). In regulating MMPs, TIMP1 plays a crucial role in extracellular matrix (ECM) composition, wound healing, and pregnancy.<br><br>The dysregulated activity of TIMP1 has been implicated in cancer. In pregnancy, TIMP1 plays a regulatory role in the process of implantation, particularly the cytotrophoblast invasion of the uterine endometrium. Additionally, it plays a role in regulating the transcriptional profile of fetal and placental tissues associated with the early stages of pregnancy. Studies attribute this role to a mechanism involving the chromatin structure at the TIMP1 promoter region, implicating new pharmaceutical possibilities for the therapeutic regulation of TIMP1. Accordingly, TIMP1 can be manipulated in vitro using techniques, like the TIMP1 knock-out. [Wiki]

Specifications

Catalog number
V3596IHC-7ML
Size / count
7 mL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
UniProt
P01033
Host
Rabbit
Immunogen
Recombinant human protein was used as the immunogen for this recombinant TIMP1 antibody.
Clonality
Monoclonal
Isotype
IgG κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the recombinant TIMP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant TIMP1 antibody is available for research use only.

Frequently Asked Questions

What is the catalog number for TIMP1 Recombinant Antibody?

The catalog number for TIMP1 Recombinant Antibody is V3596IHC-7ML.

Is TIMP1 Recombinant Antibody in stock?

TIMP1 Recombinant Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is TIMP1 Recombinant Antibody used for?

TIMP1 is an inhibitory molecule that regulates matrix metalloproteinases (MMPs), and disintegrin-metalloproteinases (ADAMs and ADAMTSs). In regulating MMPs, TIMP1 plays a crucial role in extracellular matrix (ECM) composition, wound healing, and pregnancy.<br><br>The dysregulated activity of TIMP1 h

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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