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Product details

Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture)

Catalog number HA722193

Price for HA722193

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Size / count 100 µL

About this product

Subunit beta of interleukin 12 (also known as IL-12B, natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor p40, or interleukin-12 subunit p40) is a protein subunit that in humans is encoded by the IL12B gene. IL-12B is a common subunit of interleukin 12 and interleukin 23. This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kDa cytokine receptor like subunit encoded by this gene, and a 35 kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

Specifications

Catalog number
HA722193
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CLMF antibody CLMF p40 antibody CLMF2 antibody Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody IL 12 subunit p40 antibody IL 12B antibody IL-12 subunit p40 antibody IL-12B antibody IL12 p40 antibody IL12 subunit p40 antibody IL12B antibody IL12B_HUMAN antibody interleukin 12 beta chain antibody Interleukin 12 p40 antibody Interleukin 12 subunit beta antibody Interleukin 12B antibody Interleukin-12 subunit beta antibody natural killer cell stimulatory factor 40 kD subunit antibody NK cell stimulatory factor chain 2 antibody NKSF antibody NKSF2 antibody p40 antibody
Abbreviation
Interleukin-12 subunit beta IL-12B Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40) IL-12 subunit p40 Il12b
Swiss Prot
P43432 Mouse
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant protein within Mouse IL-12B (aa 23-335)-GSGSSRGGSGSGGSGGGGSK-IL-12A (aa 23-215).
Isotype
IgG
Clone
PSH04-87
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Cap)
Positive Control
Recombinant mouse IL-12p40 protein (HA210890).
Concentration
1 mg/mL
Dilution
ELISA (Cap): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH04-88] to Mouse IL-12p40 (Detector) (HA722194) and recombinant standard Mouse IL-12p40 protein (HA210890). The reference range value is 37-3000pg/ml.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 38 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture)?

The catalog number for Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture) is HA722193.

What sizes are available for Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture)?

Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.

Is Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture) in stock?

Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mouse IL12 p40 Recombinant Rabbit Monoclonal Antibody [PSH04-87] - BSA and Azide free (Capture) used for?

Subunit beta of interleukin 12 (also known as IL-12B, natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor p40, or interleukin-12 subunit p40) is a protein subunit that in humans is encoded by the IL12B gene. IL-12B is a common subunit of interleukin 12 and interleukin 23

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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