Purified Anti-Human CD276 Antibody[6A1]

Specifications

Catalog number

AN004110P-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

CD276

Gene ID

80381

UniProt

Q5ZPR3

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD276 protein

Target

B7H; UNQ; PRO; B7-H; B7RP; B7 homolog; B7H34Ig-B7-H; PSEC;4Ig-B7-H; CD276;4Ig-B7-H3; B7-H3; B7H3; B7RP-2; B7 homolog 3; B7H34Ig-B7-H3; CD276 antigen; CD276 molecule; Costimulatory molecule; PSEC0249; UNQ309; PRO352; B7RP-2;4Ig-B7-H3; B7H3; B7-H3; CD276 antigen

Clonality

Monoclonal

Clone

6A1

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Cancer; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgG1, κ