ULK3 Rabbit Polyclonal Antibody

Catalog number ER65265

Price for ER65265

Size / count 100 µL

About this product

Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.

Specifications

Catalog number: ER65265
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: DKFZP434C131 antibody FLJ90566 antibody Serine/threonine-protein kinase ULK3 antibody Ulk3 antibody ULK3_HUMAN antibody unc 51 like kinase 3 (C. elegans) antibody Unc-51-like kinase 3 antibody
Abbreviation: ULK3; Serine/threonine-protein kinase ULK3; Unc-51-like kinase 3
Swiss Prot: Q6PHR2 Human, Q3U3Q1 Mouse, D3ZHP7 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human ULK3 aa 1-472 / 472.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, FC
Positive Control: 293T cell lysate, HeLa cell lysate, Jurkat cell lysate, mouse brain tissue lysate, rat brain tissue lysate, HeLa.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 53 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ULK3 Rabbit Polyclonal Antibody?

The catalog number for ULK3 Rabbit Polyclonal Antibody is ER65265.

What sizes are available for ULK3 Rabbit Polyclonal Antibody?

ULK3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ULK3 Rabbit Polyclonal Antibody in stock?

ULK3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ULK3 Rabbit Polyclonal Antibody used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.