Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43]

Catalog number HA721988

Price for HA721988

Size / count 100 µL

About this product

tRNA (cytosine-5-)-methyltransferase is an enzyme that in humans is encoded by the TRDMT1 gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms. It has been shown that human DNMT2 does not methylate DNA but instead methylates cytosine 38 in the anticodon loop of aspartic acid transfer RNA (tRNA (Asp)).

Specifications

Catalog number: HA721988
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: dDNMT antibody DmMT 2 antibody DmMT2 antibody DNA (cytosine 5 ) methyltransferase 2 antibody DNA (cytosine 5) methyltransferase like protein 2 antibody DNA (cytosine-5)-methyltransferase-like protein 2 antibody DNA 5 cytosine methyltransferase antibody DNA methyltransferase 2 antibody DNA methyltransferase homolog HsaIIP antibody DNA MTase homolog HsaIIP antibody Dnmt 2 antibody Dnmt2 antibody M.HsaIIP antibody MHsaIIP antibody nmt 2 antibody nmt2 antibody OTTHUMP00000045198 antibody PuMet antibody RNMT 1 antibody RNMT1 antibody TRDMT 1 antibody TRDMT_HUMAN antibody TRDMT1 antibody tRNA (cytosine 5 ) methyltransferase antibody tRNA (cytosine (38)-C (5))-methyltransferase antibody tRNA aspartic acid methyltransferase 1 antibody tRNA aspartic acid methyltransferase 1 variant 1 antibody tRNA aspartic acid methyltransferase 1 variant 2 antibody tRNA aspartic acid methyltransferase 1 variant 3 antibody tRNA aspartic acid methyltransferase 1 variant 4 antibody tRNA aspartic acid methyltransferase 1 variant 5 antibody tRNA aspartic acid methyltransferase 1 variant 8 antibody
Abbreviation: TRDMT1, DNMT2
Swiss Prot: O14717 Human
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Monkey
Immunogen: Recombinant protein within human Dnmt2 aa 1-391 / 391.
Isotype: IgG
Clone: PSH03-43
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: MDA-MB-231 cell lysate, HeLa cell lysate, 293T cell lysate, HCT 116 cell lysate, U-2 OS cell lysate, COS-1 cell lysate, MCF7, human testis tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:2,000 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 45 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43]?

The catalog number for Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43] is HA721988.

What sizes are available for Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43]?

Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43] is available in the following size(s): 100 µL.

Is Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43] in stock?

Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Dnmt2 Recombinant Rabbit Monoclonal Antibody [PSH03-43] used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.