Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector

Catalog number HA723101B

Price for HA723101B

Size / count 100 µL

About this product

Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8.

Specifications

Catalog number: HA723101B
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AIP 1 antibody AIP1 antibody API 2 antibody API2 antibody Apoptosis inhibitor 2 antibody Baculoviral IAP repeat containing 3 antibody Baculoviral IAP repeat containing protein 3 antibody Baculoviral IAP repeat-containing protein 3 antibody BIRC 3 antibody BIRC3 antibody BIRC3_HUMAN antibody C IAP2 antibody C-IAP2 antibody Cellular inhibitor of apoptosis 2 antibody cellular inhibitor of apoptosis protein 2 antibody CIAP 2 antibody CIAP2 antibody HAIP 1 antibody HAIP1 antibody HIAP 1 antibody HIAP-1 antibody HIAP1 antibody IAP homolog C antibody IAP-1 antibody Inhibitor of apoptosis protein 1 antibody MALT 2 antibody MALT2 antibody Mammalian IAP homolog C antibody MIHC antibody RING finger protein 49 antibody RNF49 antibody TNFR2 TRAF signaling complex protein 1 antibody TNFR2 TRAF signalling complex protein antibody TNFR2-TRAF-signaling complex protein 1 antibody
Abbreviation: Baculoviral IAP repeat-containing protein 3 Apoptosis inhibitor 2 (API2) Cellular inhibitor of apoptosis 2 (C-IAP2 IAP homolog C Inhibitor of apoptosis protein 1 (hIAP-1; hIAP1) RING finger protein 49 RING-type E3 ubiquitin transferase BIRC3 TNFR2-TRAF-signaling complex protein 1 BIRC3 API2, MIHC, RNF49
Swiss Prot: Q13489 Human
Cellular Locus: Cytoplasm. Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human cIAP2 aa 246-604.
Isotype: IgG
Clone: PSH09-39
Conjugation: Biotin-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Det), ELISA
Positive Control: Recombinant Human cIAP2 Protein (HA210619).
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH09-38] to Human cIAP2 antibody (Capture) (HA723098) and Recombinant Human cIAP2 protein (HA210619) as the standard. The reference range value is 78-20,000pg/ml. ;ELISA: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector?

The catalog number for Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector is HA723101B.

What sizes are available for Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector?

Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector is available in the following size(s): 100 µL.

Is Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector in stock?

Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector is currently made to order / not held in immediate stock. Contact us for lead time.

What is Biotin Conjugated Human cIAP2 Recombinant Rabbit Monoclonal Antibody [PSH09-39] - Detector used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.