KIAA0100 Recombinant Mouse Monoclonal Antibody [A0-F3-R]

About this product

Breast cancer-overexpressed gene 1 protein (KIAA0100) is a glucoprotein composed of 2,235 amino acids. KIAA0100 has four isforms (254kDa,250kDa,45kDa,25kDa).KIAA0100 is expressed in pancreas, placenta and up-regulated in breast carcinoma epithelial cells. This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain.

Specifications

Catalog number

HA601317

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Antigen MLAA-22 antibody BCOX antibody BCOX1 antibody Breast cancer-overexpressed gene 1 protein antibody CT101 antibody DKFZp686M0843 antibody K0100_HUMAN antibody KIAA0100 antibody MGC111488 antibody MGC134981 antibody UPF0378 protein KIAA0100 antibody

Abbreviation

BLTP2, BCOX1, KIAA0100

Swiss Prot

Q14667 Human

Cellular Locus

Cell membrane, Endoplasmic reticulum membrane, Mitochondrion membrane.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within Human KIAA0100 aa 1,947-2,235 / 2,235.

Isotype

IgG1

Clone

A0-F3-R

Conjugation

Non-conjugated

Type

Recombinant Mouse monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

MDA-MB-231 cell lysate, SK-Br-3 cell lysate, MCF7 cell lysate, HeLa cell lysate, A431 cell lysate, PC-3M cell lysate, LNCaP cell lysate, HeLa, human breast cancer tissue, human kidney tissue, human pancreas tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 254 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes