PSMB5 / MB1 Rabbit Polyclonal Antibody

About this product

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA500533

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

DKFZp459C139 antibody EC 3.4.25.1 antibody LMPX antibody Macropain epsilon chain antibody MB1 antibody MGC104214 antibody MGC118075 antibody MGC134464 antibody Multicatalytic endopeptidase complex epsilon chain antibody Proteasome (prosome, macropain) subunit, beta type, 5 antibody Proteasome beta 5 subunit antibody Proteasome catalytic subunit 3 antibody Proteasome chain 6 antibody Proteasome epsilon chain antibody Proteasome subunit beta type-5 antibody Proteasome subunit MB1 antibody Proteasome subunit X antibody Proteasome subunit, beta type, 5 antibody Proteasome subunit, beta-5 antibody PSB5_HUMAN antibody PSMB5 antibody PSX large multifunctional protease X antibody X antibody

Abbreviation

PSMB5, LMPX, MB1, X

Swiss Prot

P28074 Human, O55234 Mouse, P28075 Rat

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human PSMB5 aa 34-263 / 263.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

MCF7 cell lysate, PC-3M cell lysate, K-562 cell lysate, HepG2 cell lysate, LO2 cell lysate, HEK-293 cell lysate, A549 cell lysate, NIH/3T3 cell lysate, Neuro-2a cell lysate, A431, HeLa, human breast carcinoma tissue, mouse liver tissue, rat brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:2,000 ;IF-Cell: 1:200 ;FC: 1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 25 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No