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![Quinolones Recombinant Rabbit Monoclonal Antibody [PSH0-35] - BSA and Azide free — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea81207/imageurl/ha721339.webp)
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Product details
Catalog number HA721339
Price for HA721339
Size / count 100 µL
Quinolones are a class of broad-spectrum antibiotics with excellent oral bioavailability and can be used to treat a wide variety of bacterial infections. They act on bacterial type II topoisomerases, DNA gyrase, and topoisomerase IV, inhibiting their function and converting them into toxic enzymes that produce permanent double-stranded breaks in the bacterial chromosome. FDA-approved indications for certain quinolones in adults include treatment of urinary tract infections, pyelonephritis, sexually transmitted infections, prostatitis, gastrointestinal and intraabdominal infections, skin and soft tissue infections, community-acquired and nosocomial pneumonia, and bone and joint infections. Further studies are currently underway to extend the use of quinolones into other therapeutic fields, such as cancer treatment and as an anti-protozoan agent. The use of quinolones may result in higher rates of clostridium difficile infection compared to other antibiotics. In multiple animal studies, quinolones have demonstrated to accumulate in the immature articular cartilage of juvenile animals, leading to the development of arthropathies and damage to the cartilage of weight-bearing joints. There are concerns regarding the potential of permanent damage to growing cartilage in human children, but there are only limited safety studies on quinolone use in pediatric patients. In pregnant women, there are theoretical concerns that the quinolones could potentially inhibit DNA synthesis in the growing fetus, leading to fetal organ agenesis, mutagenesis, and carcinogenesis.
The catalog number for Quinolones Recombinant Rabbit Monoclonal Antibody [PSH0-35] - BSA and Azide free is HA721339.
Quinolones Recombinant Rabbit Monoclonal Antibody [PSH0-35] - BSA and Azide free is available in the following size(s): 100 µL.
Quinolones Recombinant Rabbit Monoclonal Antibody [PSH0-35] - BSA and Azide free is currently made to order / not held in immediate stock. Contact us for lead time.
Quinolones are a class of broad-spectrum antibiotics with excellent oral bioavailability and can be used to treat a wide variety of bacterial infections. They act on bacterial type II topoisomerases, DNA gyrase, and topoisomerase IV, inhibiting their function and converting them into toxic enzymes t
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.
Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.
