Product details
Catalog number HA722907
Price for HA722907
Size / count 100 µL
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal. Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells.
The catalog number for Human CD31 Recombinant Rabbit Monoclonal Antibody [PSH07-83] - BSA and Azide free (Detector) is HA722907.
Human CD31 Recombinant Rabbit Monoclonal Antibody [PSH07-83] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.
Human CD31 Recombinant Rabbit Monoclonal Antibody [PSH07-83] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for t
The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.
Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.
Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.