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Product details

ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98]

Catalog number HA722071

Price for HA722071

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Size / count 100 µL

About this product

Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE-BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.

Specifications

Catalog number
HA722071
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ACO 1 antibody ACO1 antibody ACOC_HUMAN antibody Aconitase 1 soluble antibody Aconitase antibody Aconitase1 antibody Aconitate hydratase antibody ACONS antibody Citrate hydro lyase antibody Citrate hydro-lyase antibody Cytoplasmic aconitate hydratase antibody Ferritin repressor protein antibody IRE BP 1 antibody IRE-BP 1 antibody IREB 1 antibody IREB1 antibody IREBP antibody IREBP1 antibody Iron regulatory protein 1 antibody Iron responsive element binding protein 1 antibody Iron-responsive element-binding protein 1 antibody IRP 1 antibody IRP1 antibody OTTHUMP00000045233 antibody
Abbreviation
Aconitase, IRP1, IRE-BP 1, ACO1, IREB1
Swiss Prot
P21399 Human, P28271 Mouse, Q63270 Rat
Cellular Locus
Cytoplasm, cytosol.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human ACO1 aa 1-50 / 889.
Isotype
IgG
Clone
JE63-98
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HeLa cell lysate, 293T cell lysate, HCT 116 cell lysate, mouse liver tissue lysate, rat liver tissue lysate, HeLa.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 98 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98]?

The catalog number for ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98] is HA722071.

What sizes are available for ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98]?

ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98] is available in the following size(s): 100 µL.

Is ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98] in stock?

ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ACO1 Recombinant Rabbit Monoclonal Antibody [JE63-98] used for?

Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 an

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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