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Product details

CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98]

Catalog number HA723051

Price for HA723051

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Size / count 100 µL

About this product

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell-antigen interactions. Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the MHC class I protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. In humans, both genes are located on chromosome 2 in position 2p12. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides.

Specifications

Catalog number
HA723051
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CD8b antigen antibody CD_antigen=CD8b antibody CD8 antigen 37 kDa chain antibody CD8 antigen beta polypeptide 1 (p37) antibody CD8 antigen beta polypeptide 1 antibody CD8 antigen, beta chain antibody CD8 antigen, beta polypeptide 1 (p37) antibody CD8 antigen, beta polypeptide 1 antibody CD8 beta antibody CD8b antibody CD8b molecule antibody CD8B_HUMAN antibody CD8B1 antibody Flags: Precursor antibody Leu2 antibody Ly3 antibody LYT3 antibody MGC119115 antibody OTTHUMP00000160762 antibody OTTHUMP00000160763 antibody OX 8 membrane antigen antibody P37 antibody T cell surface glycoprotein CD8 antibody T cell surface glycoprotein CD8 beta chain antibody T lymphocyte surface glycoprotein beta chain antibody T-cell surface glycoprotein CD8 beta chain antibody
Abbreviation
T-cell surface glycoprotein CD8 beta chain CD8b CD8B CD8B1
Swiss Prot
P10966 Human
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human CD8 beta aa 1-170.
Isotype
IgG
Clone
PSH08-98
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
293T transfected with CD8 beta cell lysate, 293T cells transfected with CD8 beta, human spleen tissue, human tonsil tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:20,000 ;IHC-P: 1:200-1:1,000 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 24 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98]?

The catalog number for CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98] is HA723051.

What sizes are available for CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98]?

CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98] is available in the following size(s): 100 µL.

Is CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98] in stock?

CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD8 beta Recombinant Rabbit Monoclonal Antibody [PSH08-98] used for?

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell-antigen interactions. Like the TCR, CD8 binds to a major histocompa

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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