Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R]

Catalog number HA601235

Price for HA601235

Size / count 100 µL

About this product

Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

Specifications

Catalog number: HA601235
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 39.1 antibody CK 17 antibody CK17 antibody CK-17 antibody Cytokeratin-17 antibody K17 antibody K1C17_HUMAN antibody Keratin 17 antibody keratin 17 epitope S1 antibody keratin 17 epitope S2 antibody keratin 17 epitope S4 antibody Keratin 17, type I antibody Keratin antibody Keratin type I cytoskeletal 17 antibody keratin, type i cytoskeletal 17 [version 1] antibody Keratin-17 antibody KRT17 antibody PC antibody PC2 antibody PCHC1 antibody type I cytoskeletal 17 antibody
Abbreviation: Keratin, type I cytoskeletal 17 39.1 Cytokeratin-17 CK-17 Keratin-17 K17
Swiss Prot: Q04695 Human
Cellular Locus: Cytoplasm.
Host: Mouse
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Cytokeratin 17 aa 383-432 / 432.
Isotype: IgG1
Clone: A2B10-R
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: HeLa cell lysate, A431 cell lysate, MCF7 cell lysate, HepG2 cell lysate, HeLa, human cervical cancer tissue, human lung adenocarcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R]?

The catalog number for Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R] is HA601235.

What sizes are available for Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R]?

Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R] is available in the following size(s): 100 µL.

Is Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R] in stock?

Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 17 Recombinant Mouse Monoclonal Antibody [A2B10-R] used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.