PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90]

Catalog number HA721381

Price for HA721381

Size / count 100 µL

About this product

PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-γ, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis. The "natural" substrates for PON1 appear to be lactones. However, PON1 has evolved to be a highly promiscuous enzyme capable of hydrolysing a wide variety of substrates such as lactones (including a number of important pharmaceutical agents such as statins), glucuronide drugs, thiolactones, arylesters, cyclic carbonates, organophosphorus pesticides and nerve gases such as sarin, soman and VX, oestrogen esters and lipid peroxides (oxidised lipids).

Specifications

Catalog number: HA721381
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: A esterase 1 antibody A-esterase 1 antibody Aromatic esterase 1 antibody Arylesterase 1 antibody Arylesterase B type antibody ESA antibody Esterase A antibody K 45 antibody K-45 antibody MVCD5 antibody Paraoxonase 1 antibody Paraoxonase antibody Paraoxonase B type antibody Paraoxonase, plasma antibody Paraoxonase1 antibody PON 1 antibody PON antibody PON1 antibody PON1_HUMAN antibody Serum aryldiakylphosphatase antibody Serum aryldialkylphosphatase 1 antibody Serum paraoxonase/arylesterase 1 antibody
Abbreviation: PON1
Swiss Prot: P27169 Human, P52430 Mouse, P55159 Rat
Cellular Locus: Secreted, extracellular space.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human PON1 aa 101-150 / 355.
Isotype: IgG
Clone: JE30-90
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: Human liver tissue lysate, mouse liver tissue lysate, rat liver tissue lysate, human liver carcinoma tissue, human liver tissue, mouse liver tissue, rat liver tissue, HepG2.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;FC: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 40 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90]?

The catalog number for PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90] is HA721381.

What sizes are available for PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90]?

PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90] is available in the following size(s): 100 µL.

Is PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90] in stock?

PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90] used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.