Purified Anti-Human CD27 Antibody[O323]

Specifications

Catalog number

E-AB-F11400P-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Abbreviation

CD27

Gene ID

939

UniProt

P26842

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD27 protein

Target

S152. LPFS; T-cell activation antigen CD; TNFRSF; S152.LPFS; CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2; CD27L receptor; T-cell activation antigen CD27; S152; TNFRSF7; CD 27; CD27 antigen; CD27 molecule; LPFS2; MGC20393; OTTHUMP00000238557; T cell activation antigen CD27; T cell antivation antigen S152; TNFRSF 7; TNFSF7; Tp 55; Tumor necrosis factor receptor superfamily member 7

Clonality

Monoclonal

Clone

O323

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Cancer; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgG1, κ