HTRA1 Polyclonal Antibody — image 1 of 2

Product details

HTRA1 Polyclonal Antibody

Catalog number D-AB-10103L-01

Discontinued

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Price for D-AB-10103L-01

Size / count 25 µL

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Specifications

Catalog number: D-AB-10103L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. This activity requires the integrity of the catalytic site, although it is unclear whether TGF-beta proteins are themselves degraded. By acting on TGF-beta signaling, may regulate many physiological processes, including retinal angiogenesis and neuronal survival and maturation during development. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets.
Abbreviation: HTRA1
UniProt: Q92743
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant Human HTRA1 protein expressed by E.coli
Target: Serine protease HTRA1; High-temperature requirement A serine peptidase 1; L56; Serine protease 11; PRSS11
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Signal transduction
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; IHC 1:400-1:800
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 51 kDa
Observed Molecular Weight: 51 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for HTRA1 Polyclonal Antibody?

The catalog number for HTRA1 Polyclonal Antibody is D-AB-10103L.

What sizes are available for HTRA1 Polyclonal Antibody?

HTRA1 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does HTRA1 Polyclonal Antibody come in?

HTRA1 Polyclonal Antibody is available in 2 different pack sizes.

Is HTRA1 Polyclonal Antibody in stock?

HTRA1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HTRA1 Polyclonal Antibody?

HTRA1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HTRA1 Polyclonal Antibody?

Estimated delivery time for HTRA1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HTRA1 Polyclonal Antibody?

The safety data sheet for HTRA1 Polyclonal Antibody is available here: https://789.bio/eb/COhLO8.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.