Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector)

Catalog number HA722384

Price for HA722384

Size / count 100 µL

About this product

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Specifications

Catalog number: HA722384
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Activation inducible TNFR family receptor antibody Activation-inducible TNFR family receptor antibody AITR antibody CD357 antibody GITR antibody GITR D antibody GITR-D antibody GITRD antibody Glucocorticoid induced TNFR related protein antibody glucocorticoid-induced tnf receptor ligand antibody glucocorticoid-induced tnf receptors ligand antibody Glucocorticoid-induced TNFR-related protein antibody TNF receptor superfamily activation inducible protein antibody TNFRSF 18 antibody TNFRSF18 antibody TNR18_HUMAN antibody Tumor necrosis factor receptor superfamily member 18 antibody Tumor necrosis factor receptor superfamily member 18 precursor antibody
Abbreviation: Tumor necrosis factor receptor superfamily member 18 Activation-inducible TNFR family receptor Glucocorticoid-induced TNFR-related protein CD357 TNFRSF18 AITR, GITR UNQ319/PRO364
Swiss Prot: Q9Y5U5 Human
Cellular Locus: Cell membrane, Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human GITR aa 26-162 (Extracellular).
Isotype: IgG
Clone: PSH05-64
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Det)
Positive Control: Recombinant standard Human GITR protein (HA210945).
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH05-63] to Human GITR (Capture) (HA722383) and recombinant standard Human GITR protein (HA210945). The reference range value is 37-3000pg/ml.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector)?

The catalog number for Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector) is HA722384.

What sizes are available for Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector)?

Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector) in stock?

Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human GITR Recombinant Rabbit Monoclonal Antibody [PSH05-64] - BSA and Azide free (Detector) used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.