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Product details

Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18]

Catalog number HA722806

Price for HA722806

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Size / count 100 µL

About this product

Cofilin 1 (non-muscle; n-cofilin), also known as CFL1, is a human gene, part of the ADF/cofilin family. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. One group reports that reelin signaling leads to serine3-phosphorylation of cofilin-1, and this interaction may play a role in the reelin-related regulation of neuronal migration.

Specifications

Catalog number
HA722806
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
18 kDa phosphoprotein antibody CFL 1 antibody CFL antibody CFL1 antibody COF1_HUMAN antibody Cofilin 1 antibody Cofilin 1 non muscle antibody Cofilin antibody Cofilin non muscle isoform antibody Cofilin-1 antibody epididymis secretory protein Li 15 antibody HEL-S-15 antibody non-muscle isoform antibody p18 antibody
Abbreviation
Cofilin-1 18 kDa phosphoprotein (p18) Cofilin, non-muscle isoform CFL1 CFL
Swiss Prot
P23528 Human, P45592 Rat
Cellular Locus
Nucleus matrix, Cytoplasm, cytoskeleton, Cell projection, ruffle membrane, lamellipodium membrane, lamellipodium, growth cone, axon.
Host
Rabbit
Species Reactivity
Human, Rat, Monkey
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser3 of human Cofilin aa 1-50.
Isotype
IgG
Clone
PSH07-18
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
COS-1 cell lysate, C6 cell lysate, Jurkat cell lysate, MCF7 cell lysate, A431 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 19 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18]?

The catalog number for Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18] is HA722806.

What sizes are available for Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18]?

Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18] is available in the following size(s): 100 µL.

Is Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18] in stock?

Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-Cofilin (S3) Recombinant Rabbit Monoclonal Antibody [PSH07-18] used for?

Cofilin 1 (non-muscle; n-cofilin), also known as CFL1, is a human gene, part of the ADF/cofilin family. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manne

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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