MEK6 Recombinant Rabbit Monoclonal Antibody [PSH07-86]

About this product

Dual specificity mitogen-activated protein kinase kinase 6 also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17. MAPKK 6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis.

Specifications

Catalog number

HA722917

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Dual specificity mitogen activated protein kinase kinase 6 antibody Dual specificity mitogen-activated protein kinase kinase 6 antibody MAP kinase kinase 6 antibody MAP2K6 antibody MAPK/ERK kinase 6 antibody MAPKK 6 antibody MAPKK6 antibody MEK 6 antibody MEK6 antibody Mitogen Activated Protein Kinase Kinase 6 antibody MKK 6 antibody MKK6 antibody MP2K6_HUMAN antibody PRKMK6 antibody protein kinase antibody Protein kinase mitogen activated kinase 6 antibody protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6) antibody SAPK kinase 3 antibody SAPKK-3 antibody SAPKK3 antibody SKK3 antibody Stress-activated protein kinase kinase 3 antibody

Abbreviation

MAP2K6, MEK6, MKK6, PRKMK6, SKK3

Swiss Prot

P52564 Human, P70236 Mouse,

Cellular Locus

Nucleus, Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human MEK6 aa 1-50.

Isotype

IgG

Clone

PSH07-86

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IP

Positive Control

HeLa cell lysate, A431 cell lysate, HepG2 cell lysate, HEK-293 cell lysate, NIH/3T3 cell lysate, Mouse skeletal muscle tissue lysate, Rat skeletal muscle tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 37 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes