Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL

Catalog number BNC470080-500

Price for BNC470080-500

Size / count 1x 500 µL

About this product

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e. g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470080-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ESR1
Gene ID: 2099
NCBI Gene ID: 208124
UniProt: P03372
Swiss Prot: P03372
Host: Mouse
Species Reactivity: Human
Reactivity: Estrogen Receptor, alpha
Immunogen: Recombinant fragment (around aa 2-185) of human Estrogen Receptor alpha protein (exact sequence is proprietary)
Target Antigen: Estrogen Receptor, alpha
Clonality: Monoclonal
Clone: ER506
Type: Primary
Source: Animal
Origin: Animal
Positive Control: MCF-7 Cells. Breast or Endometrial Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 67 kDa
References & Citations: Harvey JM, et. al. Journal of Clinical Oncology 1999; 17(5), 1474-1481. |Zafrani B, et. al. Histopathology 2000; 37(6), 536-545.
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL?

The catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL is BNC470080-500.

What sizes are available for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL in stock?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b9061270361e10c655/msds/bnc470080-500.pdf.

What is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), CF647 conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.