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Product details

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL

Catalog number BNUB0080-100

Price for BNUB0080-100

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Size / count 1x 100 µL

About this product

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e. g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB0080-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ESR1
Gene ID
2099
NCBI Gene ID
208124
UniProt
P03372
Swiss Prot
P03372
Host
Mouse
Species Reactivity
Human
Reactivity
Estrogen Receptor, alpha
Immunogen
Recombinant fragment (around aa 2-185) of human Estrogen Receptor alpha protein (exact sequence is proprietary)
Target Antigen
Estrogen Receptor, alpha
Clonality
Monoclonal
Clone
ER506
Type
Primary
Source
Animal
Origin
Animal
Positive Control
MCF-7 Cells. Breast or Endometrial Carcinoma.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
67 kDa
References & Citations
Harvey JM, et. al. Journal of Clinical Oncology 1999; 17(5), 1474-1481. |Zafrani B, et. al. Histopathology 2000; 37(6), 536-545.
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL?

The catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL is BNUB0080-100.

What sizes are available for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL in stock?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL?

Estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL?

The safety data sheet for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102ae5/msds/bnub0080-100.pdf.

What is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ER506), 0.2mg/mL used for?

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e. g. tamoxifen) therap

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

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