CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0201-100

Price for BNCB0201-100

Size / count 1x 100 µL

About this product

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0201-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Erythrocyte receptor; LFA-2; LFA-3 receptor; Ly-37; Lymphocyte function antigen 2; Rosette receptor; SRBC; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD2
Gene ID: 914
NCBI Gene ID: 523500
UniProt: P06729
Swiss Prot: P06729
Host: Mouse
Species Reactivity: Human
Reactivity: CD2|LFA-2|Lymphocyte Function Antigen 2
Immunogen: Human Thymocytes/Sezary T cells
Target Antigen: CD2 | LFA-2 | Lymphocyte Function Antigen 2
Clonality: Monoclonal
Clone: UMCD2
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published) |IF (published) |IHC, FFPE (published)
Positive Control: 293T or Jurkat cells. Lymph node and tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~50 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Transplant Proc (1987) 19(1):277-8. (functional studies, IP) Fert Stert (2008) 90,(3), P849.E5-849.E8. (IHC, frozen) eLife. 2018; 7: e31657. (IF, FFPE) Am J Transplant. 2019;20:88-100. (Flow)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL?

The catalog number for CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL is BNCB0201-100.

What sizes are available for CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL?

CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL in stock?

CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL?

CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD2 / Lymphocyte Function Antigen 2 (LFA-2) (UMCD2), Biotin conjugate, 0.1mg/mL used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.