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Product details

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL

Catalog number BNC680252-500

Price for BNC680252-500

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Size / count 1x 500 µL

About this product

This MAb recognizes the 56. 5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e. g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC680252-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
K1B; KRT1B; Keratin; type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT77
Gene ID
374454
NCBI Gene ID
334989
UniProt
Q7Z794
Swiss Prot
Q7Z794
Host
Mouse
Species Reactivity
Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat, Turtle
Reactivity
Cytokeratin, Acidic
Immunogen
Human epidermal keratin
Target Antigen
Cytokeratin, Acidic
Clonality
Monoclonal
Clone
AE-1
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Cytoskeleton
Positive Control
Skin or squamous cell carcinoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-56.5 kDa
References & Citations
Woodock-Mitchell J et. al. Journal of Cell Biology 1982;95:580-8. |Tseng SCG et. al. Cell 1982; 30361
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL is BNC680252-500.

What sizes are available for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL?

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL in stock?

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL?

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b2061270361e10a17b/msds/bnc680252-500.pdf.

What is Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF568 conjugate, 0.1mg/mL used for?

This MAb recognizes the 56. 5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-6

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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